American Assassin Trailer 2017 | Hollywood Movies Trailer. CBS Films and Lionsgate just released a new action-heavy trailer for American Assassin, based on the bestselling novel by Vince Flynn. The film stars Dylan O’Brien and Michael Keaton, along with Taylor Kitsch, Sanaa Lathan, Shiva Neger, and Scott Adkins. Stephen Schiff, Michael Finch, Edward Zwick, and Marshall Herskovitz adapted the book for the screen, with Michael Cuesta (Homeland, Elementary) directing the R-rated action thriller. American Assassin is set to open in theaters on September 15, 2017.